| Item Type | Name |
|
Academic Article
|
Glucuronidation of catechols by human hepatic, gastric, and intestinal microsomal UDP-glucuronosyltransferases (UGT) and recombinant UGT1A6, UGT1A9, and UGT2B7.
|
|
Academic Article
|
Human PXR variants and their differential effects on the regulation of human UDP-glucuronosyltransferase gene expression.
|
|
Academic Article
|
Glucuronidation of oxidized fatty acids and prostaglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases.
|
|
Academic Article
|
Regulation of UDP glucuronosyltransferase genes.
|
|
Academic Article
|
Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7.
|
|
Academic Article
|
A historical overview of the heterologous expression of mammalian UDP-glucuronosyltransferase isoforms over the past twenty years.
|
|
Academic Article
|
Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7.
|
|
Academic Article
|
Structure of UDP-glucuronosyltransferases in membranes.
|
|
Academic Article
|
Phenylalanine(90) and phenylalanine(93) are crucial amino acids within the estrogen binding site of the human UDP-glucuronosyltransferase 1A10.
|
|
Academic Article
|
The first aspartic acid of the DQxD motif for human UDP-glucuronosyltransferase 1A10 interacts with UDP-glucuronic acid during catalysis.
|
|
Academic Article
|
Human UDP-glucuronosyltransferase 1A5: identification, expression, and activity.
|
|
Academic Article
|
Human UGT1A8 and UGT1A10 mRNA are expressed in primary human hepatocytes.
|
|
Academic Article
|
Resveratrol is efficiently glucuronidated by UDP-glucuronosyltransferases in the human gastrointestinal tract and in Caco-2 cells.
|
|
Academic Article
|
Glucuronidation of monohydroxylated warfarin metabolites by human liver microsomes and human recombinant UDP-glucuronosyltransferases.
|
|
Academic Article
|
Preface.
|
|
Academic Article
|
Role of human UDP-glucuronosyltransferases in the biotransformation of the triazoloacridinone and imidazoacridinone antitumor agents C-1305 and C-1311: highly selective substrates for UGT1A10.
|
|
Academic Article
|
Assessing cytochrome P450 and UDP-glucuronosyltransferase contributions to warfarin metabolism in humans.
|
|
Academic Article
|
Analysis of R- and S-hydroxywarfarin glucuronidation catalyzed by human liver microsomes and recombinant UDP-glucuronosyltransferases.
|
|
Academic Article
|
A functional role for histidyl residues of the UDP-glucuronic acid carrier in rat liver endoplasmic reticulum membranes.
|
|
Academic Article
|
UDP-glucuronosyltransferases in human intestinal mucosa.
|
|
Academic Article
|
Characterization of human hepatic and extrahepatic UDP-glucuronosyltransferase enzymes involved in the metabolism of classic cannabinoids.
|
|
Academic Article
|
Human and rat liver UDP-glucuronosyltransferases are targets of ketoprofen acylglucuronide.
|
|
Academic Article
|
The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families.
|
|
Academic Article
|
Novel identification of UDP-glucuronosyltransferase 1A10 as an estrogen-regulated target gene.
|
|
Academic Article
|
Identification of UDP-glucuronosyltransferase 1A10 in non-malignant and malignant human breast tissues.
|
|
Academic Article
|
13-hydroxy- and 13-oxooctadecadienoic acids: novel substrates for human UDP-glucuronosyltransferases.
|
|
Academic Article
|
Cloning and characterization of mammalian UDP-glucose glycoprotein: glucosyltransferase and the development of a specific substrate for this enzyme.
|
|
Academic Article
|
Glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4, 5-b]pyridine by human microsomal UDP-glucuronosyltransferases: identification of specific UGT1A family isoforms involved.
|
|
Academic Article
|
Effect of retinoids on UDP-glucuronosyltransferase 2B7 mRNA expression in Caco-2 cells.
|
|
Academic Article
|
Cloning and expression of human UDP-glucuronosyltransferase (UGT) 1A8.
|
|
Academic Article
|
Conjugation of synthetic cannabinoids JWH-018 and JWH-073, metabolites by human UDP-glucuronosyltransferases.
|
|
Academic Article
|
Identification of hydroxywarfarin binding site in human UDP glucuronosyltransferase 1a10: phenylalanine90 is crucial for the glucuronidation of 6- and 7-hydroxywarfarin but not 8-hydroxywarfarin.
|
|
Academic Article
|
Interaction of periodate-oxidized UDP-glucuronic acid with recombinant human liver UDP-glucuronosyltransferase 1A6.
|
|
Academic Article
|
Glucuronidation of linoleic acid diols by human microsomal and recombinant UDP-glucuronosyltransferases: identification of UGT2B7 as the major isoform involved.
|
|
Academic Article
|
4-hydroxyretinoic acid, a novel substrate for human liver microsomal UDP-glucuronosyltransferase(s) and recombinant UGT2B7.
|
|
Academic Article
|
Linoleic acid diols are novel substrates for human UDP-glucuronosyltransferases.
|
|
Academic Article
|
Dopamine is a low-affinity and high-specificity substrate for the human UDP-glucuronosyltransferase 1A10.
|
|
Academic Article
|
Glucuronidation of estrogens and retinoic acid and expression of UDP-glucuronosyltransferase 2B7 in human intestinal mucosa.
|
|
Academic Article
|
Nuclear UDP-glucuronosyltransferases: identification of UGT2B7 and UGT1A6 in human liver nuclear membranes.
|
|
Academic Article
|
Structural and functional studies of UDP-glucuronosyltransferases.
|
|
Academic Article
|
Phenylalanine 90 and 93 are localized within the phenol binding site of human UDP-glucuronosyltransferase 1A10 as determined by photoaffinity labeling, mass spectrometry, and site-directed mutagenesis.
|
|
Academic Article
|
Photoaffinity labeling of the aglycon binding site of the recombinant human liver UDP-glucuronosyltransferase UGT1A6 with 7-azido-4-methylcoumarin.
|
|
Academic Article
|
Variability of human hepatic UDP-glucuronosyltransferase activity.
|
|
Concept
|
Uridine Diphosphate Sugars
|
|
Concept
|
Uridine Diphosphate
|
|
Concept
|
Uridine Diphosphate Glucuronic Acid
|
|
Academic Article
|
Novel resveratrol-based substrates for human hepatic, renal, and intestinal UDP-glucuronosyltransferases.
|
|
Academic Article
|
The effect of inhibitors, structurally related to UDP-glucuronic acid, on human recombinant UGT1A10
|
|
Academic Article
|
Determination of the human liver UDP-glucuronosyltransferase 2B4 domains involved in the binding of UDP-glucuronic acid using photoaffinity labeling of fusion proteins
|
|
Academic Article
|
Gambogic acid and its analogues are novel substrates for human UDP-glucuronosyltransferase and bind cannabinoid receptors CB1 and CB2
|
|
Academic Article
|
inhibitors and characterization of the active site of UDP-glucuronosyltransferase UGT*6
|
|
Academic Article
|
The glucuronidation of native and oxidized estrogens can be effectively inhibited by compounds structurally related to UDP-glucuronic acid in human recombinant UGT1A10
|
|
Academic Article
|
Human UDP-Glucuronosyltransferases: Role in modulation of pancreatic cancer cell proliferation and drug toxicity
|
|
Academic Article
|
Application of 5-azido-UDP-glucuronic acid for the characterization of human liver microsomal UDP-glucuronosyltransferase
|
|
Academic Article
|
Glucuronidation of arachidonic acid 20-HETE and prostagladin E2 by human hepatic and intestinal UDP-glucuronosyltransferases and recombinant UGT2B7
|
|
Academic Article
|
Glucuronidation of Warfarin Metabolites by human Recombinant UDP-Glucuronosyltransferases (UGTs)
|
|
Academic Article
|
Estradiol regulates the expression of UDP-glucuronosyltransferase 1A10 in normal and malignant human breast cells
|
|
Academic Article
|
Effect of high pressure treatment on the properties of human liver microsomal UDP-glucuronosyltransferase
|
|
Academic Article
|
Isolation of UDP-glucuronosyltransferase clones using specific PCR-generated probes
|
|
Academic Article
|
The effects of inhibitors structurally related to UDP-glucuronic acid on human recombinant UGT2B7 expreesesd in HK293 cells
|
|
Academic Article
|
Identification and Characterization of the UDP-glucuronic Acid and Substrate Binding Sites of Human UDP-glucuronosyltransferases: Crystallization and Photoaffinity Labeling
|
|
Academic Article
|
Transcriptional regulation of UDP-glucuronosyltransferases
|
|
Academic Article
|
Characterization of UDP-glucuronic acid binding site of recombinant human liver UGT1*6 by the photoaffinity labeling and proteolytic mapping
|
|
Academic Article
|
Comparison of bile acid glucuronidation activity in various species; solubilzation of rabbit liver caboxyl-directed bile acid UDP-glucuronosyltransferase(UDP-GT). FASEB J, 2:A581
|
|
Academic Article
|
A structure and reaction mechanism of human UDP-glucuronosyltransferases
|
|
Academic Article
|
constitutive expression of human UDP-glucuronosyltranseferases 2B7 neuyralizes the anti-proliferative effect of retinoic acod in cell culture
|
|
Academic Article
|
Targeted nanoparticle delivery of tumor suppressing UDP-glucuronosyltransferase (UGT) genes into cancer cells
|
|
Academic Article
|
Glucuronidation of hyodeoxycholic acid in human liver. Evidence for a selective role of UDP-glucuronosyltransferase 2B4
|
|
Academic Article
|
Glucuronidation of all-trans-retinoic acid and 5,6-epoxy-all-trans-retinoic acid. Activation of rat liver microsomal UDP-glucuronosyltransferase activity by alamethicin
|
|
Academic Article
|
Human liver UDP-glucuronosyltransferases 8th international Colloquium Biologie Prospectives:Drug Metabolizing Enzymes in man
|
|
Academic Article
|
Effect of acyl glucuronides of endogenous compounds on UDP-glucuronosyltransferases
|
|
Academic Article
|
Characterization of UDP-glucuronic acid transport in rat liver microsomal vesicles with photoaffinity analogs
|
|
Academic Article
|
Human UDP-glucuronosyltransferases: A Novel Role in Modulating Cytotoxicity in Cancer
|
|
Academic Article
|
Chemical modification of human UDP-glucuronosyltransferase UGT1*6 by diethyl pyrocarbonate: possible involvement of a histidine residue in the catalytic process
|
|
Academic Article
|
Phenylalanine90 is a crucial amino acid localized with the phenol binding site of human UDP-glucuronosyltransferases 1A10 as determined by photoaffinity labeling mass spectrometry and site directed mutagenesis
|
|
Academic Article
|
Human UDP-glucuronosyltransferases UGTs) 1A3 and 1A4 are induced by ligands of the aryl hydrocarbon receptor (AhR)
|
|
Academic Article
|
Synthesis and characterization of a new class of inhibitors of membrane-associated UDP-glycosyltransferases
|
|
Academic Article
|
5-Azido-UDP-Glucuronic acid: A New Affinity Probe for UDP-Glucuronic Acid-Utilizing Proteins
|
|
Academic Article
|
Photoaffinity labeling of the aglycon binding site of the human recombinant UDP-glucuronosyltransferase UGT1A6 and phenol sulfotransferase P-PST with 7-azido-4-methylcoumarin
|
|
Academic Article
|
A Functional Role for Histidyl Residues of the UDP-GlucuronicAcid Carrier in Rat Endoplasmic Reticulum Membranes
|
|
Academic Article
|
Membrane translocation and regulation of uridine diphosphate-glucuronic acid uptake in rat liver microsomal vesicles
|
|
Academic Article
|
Arginine 52 and histidine 54 located in a conserved amino-terminal hydrophobic region (LX2-R52-G-H54-X3-V-L) are important amino acids for the functional and structural integrity of the human liver UDP-glucuronosyltransferase UGT1*6
|
|
Academic Article
|
Studies on the substrate specificity of human intestinal UDP-glucuronosyltransferases 1A8 and 1A10
|
|
Academic Article
|
Application of 5-azido-UDP-glucose and 5-azido-UDP-glucuronic acid photoaffinity probes for the determination of the active site orientation of microsomal UDP-glucosyltransferases and UDP-glucuronosyltransferases
|
|
Academic Article
|
Separation and Glucuronidation of R- and S-Hydroxywarfarins by Human Recombinant UDP-Glucuronosyltransferases (UGTs)
|
|
Academic Article
|
Effects of retionds and their oxidized derivatives on UDP-glucuronosyltransferases (UGT) 2B7 and 2B15 mRNA expression in Caco-2 cells
|
|
Academic Article
|
Lithocholic acid decreases expression of UDP-glucuronosyltransferases 2B7 inCaCo2 cell but not HepG2 cells
|
|
Academic Article
|
Regulation of the Human UDP-glucuronosyltransferases 2B7
|
|
Academic Article
|
Synthesis, biotransformation and biological effects of retinoic acid glucuronide
|
|
Academic Article
|
Overview: Cyrstallography, modeling and catalytic activity of human UDP-glucuronosyltransferases
|
|
Academic Article
|
UDP-glucuronosyltranseferases as target of acylglucuronides of drugs and endogenous compounds
|
|
Academic Article
|
Biosynthesis of oxidized fatty acids and prostaglandins by human UDP-Glucuronosyltransferases
|
|
Academic Article
|
Application of photoaffinity probes for the Characterization of UDP-glucosyltransferases
|
|
Academic Article
|
Human UDP-glucuronosyltransferases involved in estrogen glucuronidation: kinetic and estrogen biniding site
|
|
Academic Article
|
Biotransformation of Abused Synthetic Cannabinoids, JWH-018 and JWH-073, by Human Cytochromes P450 and UDP-glucuronosyltransferases
|
|
Academic Article
|
Active-site orientation of UDP-glucuronosyltransferases and GLC-P-Dol synthase in rat liver microsomes
|
|
Academic Article
|
Human UDP-glucuronosyltransferases (UGTs) are involved in the metabolism of the natural resveratrol analogues arachidin-1, arachidin-3 and piceatannol
|
|
Academic Article
|
Biotransformation of abused synthetic cannabinoids in K2/Spice by human hepatic and extrahepatic UDP-glucuronosyltransferase (UGTs)
|
|
Academic Article
|
Glucuronidation of fatty acid and their oxidized derivatives by human UDP-glucuronosyltransferases
|
|
Academic Article
|
Targeted nanoparticle delivery of tumor suppressing p53 and UDP-glucuronosyltransferase (UGT) genes into breast cancer cells
|
|
Academic Article
|
Comparative characterization of UDP-glucuronic acid (UDP-GlcUA) binding-site directed inhibitors with human UGT2B7 and 1A10
|
|
Academic Article
|
UDP-glucuronosyltransferases (UDPGTs):Structural analysis of protein sequences
|
|
Academic Article
|
Production and characterization of catalytically active human liver UDP-glucuronosyltransferase as a fusion protein in E coli
|
|
Academic Article
|
UDP-glucuronic acid transport in rat liver endoplasmic reticulum: Kinetic analysis and inhibition studies
|
|
Academic Article
|
Characterization of high and low affinity components for transport of UDP-glucuronic acid in rat liver endoplasmic reticulum
|
|
Academic Article
|
Proteolytic mapping of photolabeled sulfotransferases and UGT1*6 active site peptides by tricine-SDS-page
|
|
Academic Article
|
Transcriptional regulation of UDP-glucuronosyltransferases genes
|
|
Academic Article
|
Retinoid specific UDP-Glucuronosyltransferases
|
|
Academic Article
|
Expression and regulation of UDP-Glucuronosyltransferases from the UGT1A ans UGT2B families in mice with altered PXR
|
|
Academic Article
|
Unsaturaterd fatty acids and lipoxygenase-derived monohydroxylated derivattives are novel substrates for ER and nuclear envelop localized UDP-glucuronosyltransferases
|
|
Academic Article
|
Application of photoaffinity labeling with [11,12-3H]all-trans-retinoic acid to characterization of rat liver microsomal UDP-glucuronosyltransferase(s) with activity toward retinoic acid
|
|
Academic Article
|
Biosynthesis of glucosides of 6-hydroxylated bile acid by UDP-sugar-dependent mechanism in human liver microsomes
|
|
Academic Article
|
Characterization of UDP-glucuronosyltransferases in normal and carcinogenic human breast tissue
|
|
Academic Article
|
Transport of 5-azido-UDP-glucuronic acid into human and rat liver microsomes and photolabeling of UDP-glucuronosyltransferases
|
|
Academic Article
|
Phe90 is a crucial amino acid within the estrogen biniding site of the human UDP-glucuronosyltransferase 1A10
|
|
Academic Article
|
Cloning and Expression of three human intestinal UDP-glucuronosyltransferases(UGTs): 1A5, 1A8, and 1A10
|
|
Academic Article
|
Two kinetically-distinct components of UDP-glucuronic acid transport in rat liver endoplasmic reticulum
|
|
Academic Article
|
Human UDP-Glucuronosyltransferases: Role in modulation of breast cancer cell proliferation and drug toxicity
|
|
Academic Article
|
Human UDP-glucuronosyltransferases: A Novel Role in Modulating Cytotoxicity in Cancer
|
|
Academic Article
|
Lithocholic acid medicated FXR Suppresses UDP-Glucuronosyltransferases 2B7 expression in Caco-2 cells
|
|
Academic Article
|
Biosynthesis of glucuronides of oxidized fatty acids and prostaglandins by human UDP-glucuronosyltransferases
|
|
Academic Article
|
Mono- and Di-hydroxylated fatty acid derivatives are novel substrates for human microsomal and recombinant UDP-glucuronosyltransferases
|
|
Academic Article
|
Methods in Enzymology
|
|
Academic Article
|
A novel UDP-Glc-specific glucosyltransferase catalyzing the biosynthesis of 6-O-glucosides of bile acids in human liver microsomes
|
|
Academic Article
|
Purification and characterization of a catalytically active human liver UDP-glucuronosyltransferase expressed as a fusion protein in E. coli
|
|
Academic Article
|
Affinity labeling of the human recombinant UDP-glucuronosyltransferases UGT*6 with an aldehyde derivative of UDP-glucuronic acid
|
|
Academic Article
|
Interaction of acyl glucuronides of xenobiotics and endogenous compounds with UDP-glucuronosyltransferases and cellular proteins
|
|
Academic Article
|
Induction of UDP-Glucuronosyltransferases by Endogenous Compounds
|
|
Academic Article
|
Photoaffinity labeling for evaluation of uridinyl analogs as specific inhibitors of rat liver microsomal UDP-glucuronosyltransferases
|
|
Academic Article
|
The Aspartic Acid Of the DxxD Motif Within The C-Terminal region Of Human UDP-Glucuronosyltransferase 1A10 is Critical To The Binding of UDP-Glucuronic Acid
|
|
Academic Article
|
nuclear UDP-glucuronosyltransferases
|
|
Academic Article
|
UDP-glucuronosyltransferase activity in human intestinal microsomes
|
|
Academic Article
|
Characterization of human liver microsomal UDP-glycosyltransferases using photoaffinity analogs
|
|
Academic Article
|
Separation and Glucuronidation of R- and S-Hydroxywarfarins by Human Recombinant UDP-Glucuronosyltransferases (UGTs)
|
|
Academic Article
|
Human UDP-Glucuronosyltransferases: Role in modulation of breast cancer cell proliferation and drug toxicity
|
|
Academic Article
|
Inhibitors of cell proliferation mediated by human UDP-glucuronosyltransferases 2B7(UGT2B7)
|
|
Academic Article
|
Affinity labeling of a the human recomibinant UDP-glucuronosyltransferases UGT1*6 with UDP-glucuronic acid analogs
|
|
Academic Article
|
Bile acid glucuronidation by rat liver microsomes and cDNA-expressed UDP-glucuronosyltransferases
|
|
Academic Article
|
Identification of the recombinant UDP-glucuronosyltransferase 2B7 in nuclear envelops
|
|
Academic Article
|
Specificity and purification of human hepatic UDP-glucuronosyltransferases acting on monohydroxylated short-chain bile acids Hepatology 6:1171
|
|
Academic Article
|
Isolation of UDP-glucuronosyltransferase clones using specific PCR-generated probes
|
|
Academic Article
|
Identification of the binding site of the human recombinant UDP-glucuronosyltransferases UGT1A6 by photoaffinity labeling
|
|
Academic Article
|
Characterization of retinoid glucuronidation by rat liver microsomes
|
|
Academic Article
|
alteration of UDP-glucuronosyltransferase expression in malignant human breast tissue
|
|
Academic Article
|
Conjugation of synthetic cannabinoids in K2/Spice by human UDP-glucuronosyltransferase (UGTs)
|
|
Academic Article
|
Human Hepatic and extrahepatic UDP-glucuronosyltransferase (UGTs) enzymes involved in the metabolism of cannabinoids
|
|
Academic Article
|
Photoaffinity labeling studies of the human recombinant UDP-glucuronosyltransferase, UGT1*6, with 5-azido-UDP-glucuronic acid
|
|
Academic Article
|
Glucuronidation of fatty acids and prostaglandins by human UDP-glucuronosyltransferases in Drug Metabolism and Transport
|
|
Academic Article
|
Similarities between chtochrome P450 (CYP)2C1 and UDP-glucuronosyltransferase (UGT)1A10 phenol active site residues as identified by photoaffinity labeling (PAL), MS, and homology modeling
|
|
Academic Article
|
Linoleic acid diols: Novel substrate for human liver UDP-glucuronosyltransferases
|
|
Academic Article
|
Xth International workshop on Glucuronidation and the UDP-Glucuronosyltransferases
|
|
Academic Article
|
UDP-Glucuronosyltransferases as targets of acylglucuronides of drugs and endogenous compounds
|
|
Academic Article
|
A potential role for human UDP-glucuronosyltransferase 1A4 promoter single nucleotide polymorphisms in the pharmacogenomics of tamoxifen and its derivatives.
|
|
Academic Article
|
Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines.
|
|
Grant
|
STRUCTURE-FUNCTION OF HUMAN UDP-GLUCURONOSYLTRANSFERASES
|
|
Grant
|
RETINOID UDP-GLUCURONOSYLTRANSFERASES
|
|
Grant
|
Synthetic Cannabinoid Toxicity: Role of Biotransformation
|
|
Grant
|
HUMAN HEPATIC &INTESTINAL UDP GLUCURONOSYLTRANSFERASES
|
|
Grant
|
UDP-GLCUA TRANSFERASES--SPECIFIC UDP-GLCUA TRANSPORTER
|
|
Grant
|
Structure-Function of UDP-Glucuronosyltransferases
|
|
Grant
|
UDP-GLCUA TRANFERASES--SPECIFIC UDP-GLCUA TRANSPORTER
|
|
Academic Article
|
Enzymatic analysis of glucuronidation of synthetic cannabinoid 1-naphthyl 1-(4-fluorobenzyl)-1H-indole-3-carboxylate (FDU-PB-22).
|